SCHEMBL991944

SCHEMBL991944

CN1CCC(Br)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20931143 1.00
SCHEMBL9871440 0.88 MAPT (0.30)
SCHEMBL11606981 0.86
SCHEMBL22920974 0.75
SCHEMBL23631117 0.72
SCHEMBL146924 0.72
SCHEMBL14749922 0.72
SCHEMBL6720332 0.72
SCHEMBL6715928 0.72
SCHEMBL2080415 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4973708-A TRANSDERMAL ENHANCER FOR PENETRATION OF DRUGS THROUGH THE SKIN UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1990-11-27 US claimed
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-23 US disclosed
US-20260042765-A1 PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS INCYTE CORP (US) 2026-02-12 US disclosed
EP-4676923-A1 BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS Cancer Research Technology Limited (GB) 2026-01-14 EP disclosed
WO-2025264700-A1 GIP RECEPTOR AGONIST COMPOUNDS ELI LILLY AND COMPANY (US) 2025-12-26 WO disclosed
EP-4653438-A1 MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2025-11-26 EP disclosed
EP-4619397-A1 SALT-INDUCIBLE KINASES (SIK) INHIBITORS AND METHODS OF USES THEREOF Insilico Medicine IP Limited (HK) 2025-09-24 EP disclosed
US-12415809-B2 Pyrrolotriazine compounds as tam inhibitors INCYTE CORPORATION (US) 2025-09-16 US disclosed
EP-4585265-A2 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN Takeda Pharmaceutical Company Limited (JP) 2025-07-16 EP disclosed
EP-4251620-B1 AMINO QUINAZOLINE DERIVATIVES AS P2X3 INHIBITORS CHIESI FARM SPA (IT) 2025-04-16 EP disclosed
EP-0101265-B1 NOVEL CEPHALOSPORIN COMPOUNDS AND PREPARATION THEREOF Tanabe Seiyaku Co., Ltd. (JP) 1988-06-29 EP disclosed
US-4742174-A MICROBTOCIDES TANABE SEIYAKU CO., LTD. (JP) 1988-05-03 US disclosed
US-4727071-A MICROBIOCIDES TANABE SEIYAKU CO., LTD. (JP) 1988-02-23 US disclosed
EP-0245619-A1 Novel thiazolylacetic acid derivatives and processes for preparing the same Tanabe Seiyaku Co., Ltd. (JP) 1987-11-19 EP disclosed
US-4598154-A Thiazole intermediates for cephalosporin compounds TANABE SEIYAKU CO., LTD. (JP) 1986-07-01 US disclosed
US-4598075-A ANTIMICROBIAL TANABE SEIYAKU CO., LTD. (JP) 1986-07-01 US disclosed
EP-0147181-A2 Thiazolylacetic acid derivatives and their preparation Tanabe Seiyaku Co., Ltd. (JP) 1985-07-03 EP disclosed
EP-0101265-A2 Novel cephalosporin compounds and preparation thereof Tanabe Seiyaku Co., Ltd. (JP) 1984-02-22 EP disclosed
US-4067985-A IMMUNOSUPPRESSIVE, SEDATIVE, ANTITUMOR CHEMIE GRUNENTHAL GMBH (DT) 1978-01-10 US disclosed
US-3951985-A SUBSTITUTED ORTHO-SULFOBENZOIC ACID IMIDO PYRROLIDONE, PIPERIDONE OR CAPROLACTAM CHEMIE GRUNENTHAL GMBH (DT) 1976-04-20 US disclosed