SCHEMBL9920588

SCHEMBL9920588

C1=c2nccnc2=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10172943 0.79
SCHEMBL29891586 0.57 ALDH1A1 (0.32)
SCHEMBL19239761 0.54
SCHEMBL29353635 0.54 HSP90AA1 (0.39)
SCHEMBL352077 0.54 HSP90AA1 (0.39)
SCHEMBL138622 0.54 ADORA2A (0.36)
SCHEMBL29360166 0.54 HSP90AA1 (0.39)
SCHEMBL14380284 0.54 ALDH1A1 (0.36)
SCHEMBL29357583 0.54 ADORA2A (0.36)
SCHEMBL30358616 0.54 HSP90AA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10039748-B2 PRMT1 inhibitors and uses thereof Epizyme, Inc. (US) 2018-08-07 US disclosed
US-20180162847-A1 PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF Epizyme, Inc. (US) 2018-06-14 US disclosed
US-20180105497-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2018-04-19 US disclosed
US-9943504-B2 Arginine methyltransferase inhibitors and uses thereof Epizyme, Inc. (US) 2018-04-17 US disclosed
US-9917260-B2 Compounds with terminal heteroarylcyanovinylene groups and their use in organic solar cells BASF SE (DE) 2018-03-13 US disclosed
US-20180047908-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed
US-9868703-B2 PRMT1 inhibitors and uses thereof Epizyme, Inc. (US) 2018-01-16 US disclosed
US-20170291905-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2017-10-12 US disclosed
US-20170280720-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2017-10-05 US disclosed
US-20170267642-A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2017-09-21 US disclosed
US-20110147719-A1 ELECTRICALLY CONDUCTIVE POLYMER COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-23 US disclosed
US-20110114925-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES HSU CHE-HSIUNG 2011-05-19 US disclosed
US-20110042688-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-24 US disclosed
US-20100247923-A1 ELECTRICALLY CONDUCTIVE POLYMER COMPOSITIONS AND FILMS MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-30 US disclosed
US-20100213446-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-26 US disclosed
US-20100207109-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E.I.DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 US disclosed
US-20100187982-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 US disclosed
US-20100187509-A1 VINYLPHENOXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 US disclosed
US-20090114884-A1 AQUEOUS DISPERSIONS OF ELECTRICALLY CONDUCTING POLYMERS CONTAINING HIGH BOILING SOLVENT AND ADDITIVES LG CHEM, LTD. (KR) 2009-05-07 US disclosed
US-20080283800-A1 ELECTRICALLY CONDUCTIVE POLYMER COMPOSITIONS AND FILMS MADE THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY 2008-11-20 US disclosed