Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917278 | 0.86 | PIK3CD (0.51) | PIK3CDSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL9917276 | 0.81 | PIK3CD (0.46) | PIK3CDSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL4581970 | 0.77 | L3MBTL1 (0.48) | PIK3CDSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL8524128 | 0.77 | PIK3CD (0.46) | PIK3CDSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL1978043 | 0.76 | PIK3CD (0.51) | PIK3CDSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL9126070 | 0.76 | SMN1; SMN2 (0.45) | PIK3CDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL14488847 | 0.76 | PIK3CD (0.47) | PIK3CDSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL9917277 | 0.76 | PIK3CD (0.55) | PIK3CDKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL1635359 | 0.75 | PIK3CD (0.41) | PIK3CDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL10513 | 0.75 | PIK3CD (0.52) | PIK3CDSMN1; SMN2KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148534-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-14 | — | — | US | disclosed |
| US-20100015093-A1 | Methods and compositions of treating a flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148534-A1 | METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION | EIF2AK2, NSUN3, NSUN2 | PIK3CD 2405/4885SMN1; SMN2 2247/4885KMT2A 2858/4885 |
| US-20100015093-A1 | Methods and compositions of treating a flaviviridae family viral infection | EIF2AK2, NSUN3, NSUN2 | PIK3CD 2405/4885SMN1; SMN2 2247/4885KMT2A 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.