Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL465908 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL9625167 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL4933917 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL1832445 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL292514 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL3199266 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL7090995 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL4784041 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL2031974 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRHSD17B10TDP1 | |
| Methylene Chloride SCHEMBL948 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425661-A | Macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2024-01-19 | — | — | CN | disclosed |
| CN-105308504-B | Lighographic printing plate precursor | 爱克发有限公司 | 2019-12-03 | — | — | CN | disclosed |
| CN-109476705-A | novel cyclosporin derivatives and use thereof | 美国科技环球有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-106661013-A | 4,5-dihydroisoxazole derivatives as NAMPT inhibitors | 奥瑞基尼探索技术有限公司 | 2017-05-10 | — | — | CN | disclosed |
| US-9568822-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2017-02-14 | — | — | US | disclosed |
| CN-105960246-A | Novel cyclosporin derivatives and use thereof | 美国科技环球有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-103249424-B | For treating and preventing the novel cyclosporin derivatives of virus infection | 河北鲲翔济世医药科技有限公司 | 2016-08-10 | — | — | CN | disclosed |
| US-20160116841-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | ECO3 BV (BE) | 2016-04-28 | — | — | US | disclosed |
| CN-105308504-A | A lithographic printing plate precursor | AGFA GRAPHICS NV | 2016-02-03 | — | — | CN | disclosed |
| CN-103724328-B | Cyclic pyrimidin-4-the methane amide of inflammation, asthma and COPD is used for the treatment of as CCR2 receptor antagonist | BOEHRINGER INGELHEIM INT (DE) | 2015-10-14 | — | — | CN | disclosed |
| US-5145842-A | Protein kinase c. modulators. d. | ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) | 1992-09-08 | — | — | US | disclosed |
| US-5093337-A | SUBSTITUTED DERIVATIVES OF 20,21-DINOREBURNAMENINE, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1992-03-03 | — | — | US | disclosed |
| WO-1992002484-A1 | PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY | ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) | 1992-02-20 | — | — | WO | disclosed |
| EP-0455271-A2 | Anti-inflammatory compositions | PROCYON PHARMACEUTICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4956465-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| US-4886802-A | ANALGESICS | ROUSSEL UCLAF (FR) | 1989-12-12 | — | — | US | disclosed |
| EP-0310622-A1 | ANTI-INFLAMMATORY COMPOSITIONS. | ALDER RES CENTER CORP (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1987007599-A2 | ANTI-INFLAMMATORY COMPOSITIONS | ALDER RESEARCH CENTER CORPORATION (US) | 1987-12-17 | — | — | WO | disclosed |
| WO-1985000167-A1 | NEW RADIOPROTECTOR AGENTS HAVING AN AMINO-THIOALKYL STRUCTURE AND PREPARATION METHOD THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1985-01-17 | — | — | WO | disclosed |
| EP-0131500-A1 | Radioprotector agents with an aminothioalkyl structure, and process for their preparation | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1985-01-16 | — | — | EP | disclosed |