Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17225693 | 0.87 | KDM4E (0.67) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL19143451 | 0.84 | KDM4E (0.62) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL9905367 | 0.81 | KDM4E (0.59) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL3721409 | 0.80 | KDM4E (0.67) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL1314977 | 0.80 | KDM4E (0.67) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL31434726 | 0.80 | KDM4E (0.67) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL19143309 | 0.79 | KDM4E (0.61) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL9923080 | 0.79 | KDM4E (0.61) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL1424929 | 0.78 | KDM4E (1.00) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL9905485 | 0.76 | KDM4E (0.61) | KDM4ERAB9ANPC1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216798-A2 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2017-09-13 | — | — | EP | disclosed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |