Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923906 | 0.85 | MMP13 (0.32) | MMP13KDM4EMCOLN3 | |
| SCHEMBL15303190 | 0.78 | KDM4E (0.31) | MMP13KDM4EMCOLN3 | |
| SCHEMBL22670005 | 0.78 | KDM4E (0.31) | MMP13KDM4EMCOLN3 | |
| SCHEMBL9923868 | 0.78 | AR (0.39) | MMP13KDM4EMCOLN3 | |
| SCHEMBL9900799 | 0.76 | AR (0.39) | MMP13KDM4EMCOLN3 | |
| SCHEMBL9923887 | 0.75 | AR (0.38) | MMP13KDM4EMCOLN3 | |
| SCHEMBL15303582 | 0.73 | MMP13 (0.31) | MMP13 | |
| SCHEMBL20906300 | 0.72 | AR (0.39) | MMP13KDM4EMCOLN3 | |
| SCHEMBL30939546 | 0.72 | AR (0.42) | MMP13KDM4EMCOLN3 | |
| SCHEMBL9901069 | 0.72 | AR (0.42) | MMP13KDM4EMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |