Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905729 | 0.92 | AAK1 (0.38) | KMT2ALTA4HHTR2CHTR2BALDH1A1 | |
| SCHEMBL9924209 | 0.88 | XIAP (0.40) | XIAPKMT2ALTA4HHTR2CHTR2B | |
| SCHEMBL15303645 | 0.86 | HTR2C (0.38) | KMT2AHTR2CHTR2BALDH1A1POLB | |
| SCHEMBL15303634 | 0.85 | HTR2C (0.36) | KMT2AHTR2CHTR2BALDH1A1MEN1 | |
| SCHEMBL15306146 | 0.85 | MEN1 (0.37) | KMT2AHTR2CHTR2BMEN1 | |
| SCHEMBL29438023 | 0.82 | CA12 (0.40) | KMT2AHTR2CHTR2BALDH1A1POLB | |
| SCHEMBL19376289 | 0.82 | KMT2A (0.34) | KMT2ALTA4HHTR2CHTR2BALDH1A1 | |
| SCHEMBL9923819 | 0.82 | CA12 (0.40) | KMT2AHTR2CHTR2BALDH1A1POLB | |
| SCHEMBL15303103 | 0.81 | AAK1 (0.38) | KMT2ALTA4HHTR2CHTR2BALDH1A1 | |
| SCHEMBL21116317 | 0.80 | HTR2C (0.34) | KMT2AHTR2CHTR2BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |