Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303103 | 0.90 | AAK1 (0.38) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL9924038 | 0.88 | XIAP (0.38) | XIAPKMT2AALDH1A1POLBHTR2C | |
| SCHEMBL15303177 | 0.83 | HTR2C (0.39) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL20906305 | 0.83 | HTR2C (0.39) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL9924210 | 0.80 | CA12 (0.41) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL29438007 | 0.80 | CA12 (0.41) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL19376291 | 0.80 | KMT2A (0.34) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL9905729 | 0.79 | AAK1 (0.38) | KMT2AALDH1A1POLBHTR2CHTR2B | |
| SCHEMBL9905746 | 0.78 | KEAP1 (0.51) | KMT2AALDH1A1POLBMEN1SMN1; SMN2 | |
| SCHEMBL1979857 | 0.76 | KEAP1 (0.55) | XIAPKMT2AALDH1A1POLBHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |