SCHEMBL992478

SCHEMBL992478

C=Cc1ccc([Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.36
HDAC8 Q9BY41 2/20 0.35
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TRPA1 O75762 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31494225 0.90 ALDH1A1 (0.41) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL5080699 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5701522 0.84 ALDH1A1 (0.42) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL5958178 0.83 ALDH1A1 (0.46) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL13651182 0.83 ALDH1A1 (0.46) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL8736147 0.83 SMN1; SMN2 (0.36) ALDH1A1TRPA1TDP1
SCHEMBL8736149 0.83 SMN1; SMN2 (0.36) ALDH1A1TRPA1TDP1
SCHEMBL10535681 0.82
SCHEMBL21667308 0.79 ALDH1A1 (0.41) ALDH1A1TSHRHDAC8CHRNB2CHRNB4
SCHEMBL5701945 0.79 ALDH1A1 (0.41) ALDH1A1TSHRHDAC8CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683790-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-01-28 EP claimed
CN-119875000-A Method for reducing the residual monomer content in a polymer composition, composition capable of free radical polymerization, method for producing a polymer, polymer and use 沈阳康恩德医疗科技有限公司 2025-04-25 CN claimed
CN-119638918-A Colored silicon polymer material and preparation method thereof 江苏天眼医药科技股份有限公司 2025-03-18 CN claimed
CN-119591809-A High-water-content high-oxygen-permeability silicon hydrogel, contact lens and preparation method of contact lens 甘肃天后光学科技有限公司 2025-03-11 CN claimed
CN-119569962-A Silicon polymer material and preparation method thereof 烟台爱博诺德医用材料有限公司 2025-03-07 CN claimed
WO-2024194826-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-09-26 WO claimed
US-20240316886-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-09-26 US claimed
EP-1945231-B1 CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL PARTNERS LLP (US) 2021-11-10 EP claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
US-8986725-B2 Silicone-peroxide compositions for long-term, controlled oxygen release UNIVERSITY OF MIAMI (US) 2015-03-24 US claimed
US-20120114729-A1 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2012-05-10 US claimed
US-20110015099-A1 NON BIO-ADHESIVE POLYMER COATING COMPOSITION, ARTICLES AND DEVICES THEREOF GENERAL ELECTRIC COMPANY (US) 2011-01-20 US claimed
WO-2010121024-A2 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE UNIVERSITY OF MIAMI (US) 2010-10-21 WO claimed
US-20090210002-A1 METHOD OF FORMING A CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL ROCHAL INDUSTRIES LLP (US) 2009-08-20 US claimed
US-20070041935-A1 Polymerizable cyanoacrylate monomer and volatile liquid selected from linear and cyclic siloxanes, polydimethylsiloxanes, isooctane, and octane; kits ROCHAL PARTNERS LLP 2007-02-22 US claimed
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP claimed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US claimed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US claimed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP claimed
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US claimed