Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GZMB | P10144 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22697192 | 0.88 | GZMB (0.56) | GZMB | |
| SCHEMBL22697125 | 0.87 | GZMB (0.59) | GZMB | |
| SCHEMBL21186375 | 0.84 | GZMB (0.54) | GZMB | |
| SCHEMBL26167009 | 0.84 | GZMB (0.53) | GZMB | |
| SCHEMBL21186314 | 0.82 | GZMB (0.53) | GZMB | |
| SCHEMBL9904628 | 0.82 | GZMB (0.53) | GZMB | |
| SCHEMBL26418868 | 0.81 | GZMB (0.56) | GZMB | |
| SCHEMBL22697083 | 0.81 | GZMB (0.65) | GZMB | |
| SCHEMBL21186420 | 0.81 | GZMB (0.56) | GZMB | |
| SCHEMBL22697180 | 0.80 | GZMB (0.77) | GZMB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076985-A2 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-06-14 | — | — | WO | disclosed |