SCHEMBL9925818

CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)NCC1=CNNN1)C3

nearest known ligand 0.73

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	GZMB	P10144	20/20	0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9925798	0.87	GZMB (0.72)	GZMB
SCHEMBL9925685	0.86	GZMB (0.78)	GZMB
SCHEMBL9925816	0.85	GZMB (0.77)	GZMB
SCHEMBL21186451	0.85	GZMB (0.77)	GZMB
SCHEMBL9925826	0.85	GZMB (0.75)	GZMB
SCHEMBL5917113	0.85	GZMB (0.72)	GZMB
SCHEMBL5917103	0.85	GZMB (0.72)	GZMB
SCHEMBL15485117	0.85	GZMB (0.79)	GZMB
SCHEMBL9925819	0.85	GZMB (0.81)	GZMB
SCHEMBL15485374	0.85	GZMB (0.76)	GZMB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012076985-A2	GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING	THE UNIVERSITY OF BRITISH COLUMBIA (CA)	2012-06-14	—	—	WO	disclosed