Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884944 | 1.00 | XDH (0.36) | XDHADORA3ADORA2AADORA1 | |
| SCHEMBL9884947 | 1.00 | XDH (0.36) | XDHADORA3ADORA2AADORA1 | |
| SCHEMBL9925923 | 0.86 | LRRK2 (0.38) | XDHADORA3ADORA2AADORA1 | |
| SCHEMBL12186857 | 0.86 | LRRK2 (0.38) | XDHADORA3ADORA2AADORA1 | |
| SCHEMBL9884946 | 0.86 | LRRK2 (0.38) | XDHADORA3ADORA2AADORA1 | |
| SCHEMBL9885035 | 0.84 | NPSR1 (0.32) | — | |
| SCHEMBL10264365 | 0.84 | NPSR1 (0.32) | — | |
| SCHEMBL251985 | 0.84 | NPSR1 (0.32) | — | |
| SCHEMBL252006 | 0.84 | ADORA2A (0.42) | XDHADORA3ADORA2AADORA1 | |
| SCHEMBL10264084 | 0.83 | TLR8 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149701-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. | 2012-06-14 | — | — | US | disclosed |
| US-20120059000-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | INFINITY PHARMACEUTICALS, INC. | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059000-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | MAP3K13, AKT3, PIK3CA | XDH 3120/4885ADORA3 903/4885ADORA2A 1787/4885 |
| US-20120149701-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, AKT3, PIK3C2A | XDH 2416/4885ADORA3 366/4885ADORA2A 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.