SCHEMBL9925975

SCHEMBL9925975

Cc1cc(C)c[n+](CCCC[n+]2cc(C)cc(C)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.48
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ABCB11 O95342 1/20 0.36
ESR1 P03372 1/20 0.36
PGR P06401 1/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30875788 0.97 HTT (0.46) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL4403547 0.97 HTT (0.52) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL9162381 0.97 HTT (0.52) HTTMEN1TP53CYP1A2CYP2D6
Water SCHEMBL31247994 0.97 HTT (0.46) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL9160448 0.97 HTT (0.52) HTTMEN1TP53CYP1A2CYP2D6
Iodide SCHEMBL9154731 0.95 HTT (0.50) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL6114986 0.94 HTT (0.43) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL4066524 0.93 HTT (0.59) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL4065006 0.91 HTT (0.63) HTTMEN1TP53CYP1A2CYP2D6
SCHEMBL5300249 0.91 HTT (0.63) HTTMEN1TP53CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839591-B2 Anionic dye or brightener bearing an ammonium or phosphonium counterion, dye composition comprising them and process for dyeing keratin fibres using these dyes L'OREAL (FR) 2017-12-12 US disclosed
US-20150113742-A1 ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES L'OREAL (FR) 2015-04-30 US disclosed
EP-2463266-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE Wako Pure Chemical Industries, Ltd. (JP) 2012-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150113742-A1 ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES KRT18, IK, COL14A1 HTT 3494/4885MEN1 2069/4885TP53 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.