Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162381 | 1.00 | HTT (0.52) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL9160448 | 1.00 | HTT (0.52) | HTTMEN1TP53CYP1A2CYP2D6 | |
| Iodide SCHEMBL9154731 | 0.97 | HTT (0.50) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL9925975 | 0.97 | HTT (0.48) | HTTMEN1TP53CYP1A2CYP2D6 | |
| Water SCHEMBL31247994 | 0.95 | HTT (0.46) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL30875788 | 0.95 | HTT (0.46) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL5297727 | 0.93 | HTT (0.63) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL4068830 | 0.93 | HTT (0.63) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL5300249 | 0.93 | HTT (0.63) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL4058153 | 0.93 | HTT (0.63) | HTTMEN1TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178678-B2 | Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-03-18 | — | — | US | disclosed |
| EP-0367147-B1 | Charge transfer complex and solid electrolytic capacitor employing the same | JAPAN CARLIT CO LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-4982312-A | N,N-ALKYLENE-DI-3,5-LUTIDINE COMPLEXEED WITH 7,7,8,8-TETRACYANOQUINODIMETHAN | THE JAPAN CARLIT CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0367147-A2 | Charge transfer complex and solid electrolytic capacitor employing the same | THE JAPAN CARLIT CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | CHRNA2, CHRNA5, CHRNA4 | HTT 603/4885MEN1 4255/4885TP53 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.