⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14381777 | 0.77 | — | — | |
| SCHEMBL7863085 | 0.77 | — | — | |
| SCHEMBL12335749 | 0.77 | SELL (0.35) | — | |
| SCHEMBL25449563 | 0.76 | PTGS1 (0.33) | — | |
| SCHEMBL12706623 | 0.72 | — | — | |
| SCHEMBL9530427 | 0.72 | — | — | |
| SCHEMBL22826706 | 0.69 | TRPA1 (0.35) | — | |
| SCHEMBL11520288 | 0.67 | — | — | |
| SCHEMBL8929358 | 0.67 | CYP3A4 (0.43) | — | |
| SCHEMBL11449568 | 0.67 | SMN1; SMN2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836180-B1 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI SA (FR) | 2012-06-13 | — | — | EP | disclosed |