Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849508 | 1.00 | LMNA (0.48) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL4849270 | 1.00 | LMNA (0.48) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL4847578 | 1.00 | LMNA (0.48) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL4849442 | 1.00 | LMNA (0.48) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL9926132 | 0.95 | LMNA (0.48) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL3654573 | 0.94 | LMNA (0.46) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL4218737 | 0.94 | LMNA (0.46) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL3647992 | 0.94 | LMNA (0.46) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL3647991 | 0.94 | LMNA (0.46) | LMNAUSP2L3MBTL1TSHRMAPK1 | |
| SCHEMBL13987603 | 0.91 | LMNA (0.47) | LMNAUSP2L3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836180-B1 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI SA (FR) | 2012-06-13 | — | — | EP | disclosed |
| US-7468369-B2 | Sulfonyl pyrrolidines, method for producing the same and their use as drugs | SANOFI-AVENTIS (FR) | 2008-12-23 | — | — | US | disclosed |
| US-7468369-B2 | Sulfonyl pyrrolidines, method for producing the same and their use as drugs | SANOFI-AVENTIS (FR) | 2008-12-23 | — | — | US | disclosed |