Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 12/20 | 0.45 |
| ▸ | TNKS | O95271 | 10/20 | 0.45 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901703 | 0.81 | TNKS2 (0.68) | TNKS2TNKSSULT2A1 | |
| SCHEMBL9901707 | 0.81 | TNKS2 (0.68) | TNKS2TNKSSULT2A1 | |
| SCHEMBL15452796 | 0.76 | TNKS2 (0.43) | TNKS2TNKSSULT2A1 | |
| SCHEMBL9904973 | 0.76 | TNKS2 (0.43) | TNKS2TNKSSULT2A1 | |
| SCHEMBL9905448 | 0.74 | TNKS2 (0.39) | TNKS2TNKSSULT2A1CYP2C9 | |
| SCHEMBL9905446 | 0.74 | TNKS2 (0.39) | TNKS2TNKSSULT2A1CYP2C9 | |
| SCHEMBL15449865 | 0.66 | TNKS2 (0.79) | TNKS2TNKSSULT2A1CYP3A4CYP2C9 | |
| SCHEMBL23059592 | 0.63 | TNKS2 (0.75) | TNKS2TNKSSULT2A1CYP3A4CYP2C9 | |
| SCHEMBL15449806 | 0.63 | TNKS2 (0.62) | TNKS2TNKSSULT2A1 | |
| SCHEMBL9926183 | 0.63 | TNKS2 (0.46) | TNKS2TNKSSULT2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |