Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 9/20 | 0.46 |
| ▸ | TNKS | O95271 | 8/20 | 0.46 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452796 | 0.88 | TNKS2 (0.43) | TNKS2TNKSSULT2A1ALDH1A1MAPT | |
| SCHEMBL9904973 | 0.88 | TNKS2 (0.43) | TNKS2TNKSSULT2A1ALDH1A1MAPT | |
| SCHEMBL9901468 | 0.85 | TNKS (0.63) | TNKS2TNKSSULT2A1PRKAA2ALDH1A1 | |
| SCHEMBL9901470 | 0.85 | TNKS (0.63) | TNKS2TNKSSULT2A1PRKAA2ALDH1A1 | |
| SCHEMBL9926208 | 0.83 | TNKS (0.41) | TNKS2TNKSSULT2A1GAA | |
| SCHEMBL9926243 | 0.78 | TNKS (0.62) | TNKS2TNKSSULT2A1PRKAA2EPHX2 | |
| SCHEMBL9905418 | 0.77 | TNKS (0.52) | TNKS2TNKSSULT2A1GAAALDH1A1 | |
| SCHEMBL9905416 | 0.77 | TNKS (0.52) | TNKS2TNKSSULT2A1GAAALDH1A1 | |
| SCHEMBL15452817 | 0.70 | TNKS (0.51) | TNKS2TNKSSULT2A1PRKAA2EPHX2 | |
| SCHEMBL9905223 | 0.70 | TNKS (0.62) | TNKS2TNKSSULT2A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |