Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 6/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.41 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15449870 | 0.83 | TNKS (0.46) | TNKSTNKS2SULT2A1P2RX7KMT2A | |
| SCHEMBL9926183 | 0.83 | TNKS2 (0.46) | TNKSTNKS2SULT2A1GAA | |
| SCHEMBL9905448 | 0.82 | TNKS2 (0.39) | TNKSTNKS2SULT2A1CYP1A2CYP2C9 | |
| SCHEMBL9905446 | 0.82 | TNKS2 (0.39) | TNKSTNKS2SULT2A1CYP1A2CYP2C9 | |
| SCHEMBL9902075 | 0.79 | TNKS (0.61) | TNKSTNKS2SULT2A1KMT2ACA2 | |
| SCHEMBL9902076 | 0.79 | TNKS (0.61) | TNKSTNKS2SULT2A1KMT2ACA2 | |
| SCHEMBL9904973 | 0.70 | TNKS2 (0.43) | TNKSTNKS2SULT2A1KMT2A | |
| SCHEMBL15452796 | 0.70 | TNKS2 (0.43) | TNKSTNKS2SULT2A1KMT2A | |
| SCHEMBL9905416 | 0.69 | TNKS (0.52) | TNKSTNKS2SULT2A1GAA | |
| SCHEMBL9905418 | 0.69 | TNKS (0.52) | TNKSTNKS2SULT2A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |