Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9926282 | 0.86 | PDE10A (0.61) | PDE10A | |
| SCHEMBL9904136 | 0.84 | PDE10A (0.63) | PDE10AALDH1A1MAPTHPGD | |
| SCHEMBL9926295 | 0.81 | PDE10A (0.53) | PDE10A | |
| SCHEMBL9106457 | 0.78 | PDE10A (0.57) | PDE10A | |
| SCHEMBL9106529 | 0.78 | PDE10A (0.61) | PDE10A | |
| SCHEMBL9107492 | 0.78 | PDE10A (0.52) | PDE10AALDH1A1MAPTHPGD | |
| SCHEMBL9107651 | 0.78 | PDE10A (0.64) | PDE10A | |
| SCHEMBL9105538 | 0.77 | PDE10A (0.63) | PDE10A | |
| SCHEMBL9107086 | 0.77 | PDE10A (0.78) | PDE10A | |
| SCHEMBL9904256 | 0.76 | PDE10A (0.60) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076430-A1 | TRIAZOLOPYRIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-14 | — | — | WO | disclosed |