Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9108884 | 0.91 | PDE10A (0.65) | PDE10A | |
| SCHEMBL10267145 | 0.90 | PDE10A (0.63) | PDE10A | |
| SCHEMBL9926282 | 0.87 | PDE10A (0.61) | PDE10A | |
| SCHEMBL9107086 | 0.81 | PDE10A (0.78) | PDE10A | |
| SCHEMBL9926272 | 0.81 | PDE10A (0.47) | PDE10A | |
| SCHEMBL9107144 | 0.80 | PDE10A (0.78) | PDE10A | |
| SCHEMBL9107438 | 0.80 | PDE10A (0.63) | PDE10A | |
| SCHEMBL9105589 | 0.80 | PDE10A (0.73) | PDE10A | |
| SCHEMBL9104717 | 0.80 | PDE10A (0.79) | PDE10A | |
| SCHEMBL9109646 | 0.80 | PDE10A (0.79) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076430-A1 | TRIAZOLOPYRIDINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-14 | — | — | WO | disclosed |