Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163809 | 0.84 | KIF11 (0.46) | KIF11DNMT1 | |
| SCHEMBL12846954 | 0.80 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL29947864 | 0.77 | KIF11 (0.53) | KIF11DNMT1 | |
| SCHEMBL10420532 | 0.77 | KIF11 (0.53) | KIF11DNMT1 | |
| SCHEMBL30408374 | 0.76 | KIF11 (0.56) | KIF11DNMT1 | |
| SCHEMBL20202837 | 0.76 | KIF11 (0.56) | KIF11DNMT1 | |
| SCHEMBL4410619 | 0.76 | KIF11 (0.56) | KIF11DNMT1 | |
| SCHEMBL9926339 | 0.76 | KIF11 (0.44) | KIF11DNMT1 | |
| SCHEMBL5020894 | 0.76 | KIF11 (0.44) | KIF11DNMT1 | |
| SCHEMBL18054925 | 0.75 | KIF11 (0.51) | KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149648-A1 | THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149648-A1 | THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES | PCNA, MKI67, NFATC1 | KIF11 2051/4885TAAR1 4668/4885SLC18A2 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.