Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15924562 | 0.87 | GRIN2B (0.39) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL19614453 | 0.87 | GRIN2B (0.39) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL19614479 | 0.87 | GRIN2B (0.39) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL14343714 | 0.84 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL14343716 | 0.84 | GRIN2B (0.40) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL15665671 | 0.82 | GRIN2B (0.39) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL3514059 | 0.82 | GRIN2B (0.37) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL7264298 | 0.82 | GRIN2B (0.37) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 | |
| SCHEMBL706532 | 0.82 | CHRM2 (0.39) | GRIN2BGRIN2CCTSKSMN1; SMN2JAK3 | |
| SCHEMBL7258557 | 0.82 | GRIN2B (0.37) | GRIN2BGRIN2CCTSKUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011483-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-01-27 | — | — | WO | disclosed |