Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 3/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992656 | 1.00 | HSD11B1 (0.39) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL4805367 | 0.86 | HSD11B1 (0.38) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL912312 | 0.85 | HSD11B1 (0.38) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL4804600 | 0.85 | HSD11B1 (0.38) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL912313 | 0.85 | HSD11B1 (0.38) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL4804604 | 0.85 | HSD11B1 (0.38) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL190837 | 0.85 | HSD11B1 (0.47) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL24449608 | 0.84 | HSD11B1 (0.40) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL24448742 | 0.84 | HSD11B1 (0.40) | HSD11B1ASGR1JAK2JAK1JAK3 | |
| SCHEMBL23696267 | 0.84 | NR1H2 (0.43) | HSD11B1ASGR1JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277882-A1 | Pipéridinic compounds, process for their préparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-26 | — | — | EP | disclosed |