SCHEMBL9927399

SCHEMBL9927399

COCCOC(=O)c1cccc(C(C)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CREBBP Q92793 1/20 0.47
HPGD P15428 3/20 0.47
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
HSD17B10 Q99714 1/20 0.46
LMNA P02545 3/20 0.46
SERPINE1 P05121 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
RAB9A P51151 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13642472 0.95 SMN1; SMN2 (0.51) TSHRSMN1; SMN2MEN1KMT2ACREBBP
SCHEMBL17798298 0.93 TSHR (0.61) TSHRSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL13974641 0.88 TSHR (0.56) TSHRSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL14579728 0.88 SMN1; SMN2 (0.47) TSHRSMN1; SMN2MEN1KMT2ACREBBP
SCHEMBL23471094 0.87 TSHR (0.54) TSHRSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9918168 0.85 TSHR (0.49) TSHRSMN1; SMN2MEN1KMT2AHPGD
SCHEMBL21015808 0.83 TSHR (0.50) TSHRSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL9918169 0.82 TSHR (0.56) TSHRSMN1; SMN2KMT2AHPGDALDH1A1
SCHEMBL14001767 0.82 TSHR (0.56) TSHRSMN1; SMN2KMT2AHPGDALDH1A1
SCHEMBL11782148 0.82 SMN1; SMN2 (0.66) TSHRSMN1; SMN2MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239986-A1 COPOLYESTER AND HOT MELT ADHESIVE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-07-18 US disclosed
US-20150198528-A1 ASSAY DETECTION SYSTEM XEN BIOFLUIDX, INC. (US) 2015-07-16 US disclosed
US-20120149128-A1 ASSAYS AND ASSAY DEVICES XEN BIOFLUIDX, INC. 2012-06-14 US disclosed