Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17798298 | 0.95 | TSHR (0.61) | TSHRSMN1; SMN2SERPINE1LMNAMEN1 | |
| SCHEMBL13642472 | 0.94 | SMN1; SMN2 (0.51) | TSHRSMN1; SMN2ABCB11CYP3A4ADRA2B | |
| SCHEMBL15430829 | 0.91 | L3MBTL1 (0.52) | TSHRSMN1; SMN2ABCB11CYP3A4ADRA2B | |
| SCHEMBL23471094 | 0.88 | TSHR (0.54) | TSHRSMN1; SMN2SERPINE1LMNAMEN1 | |
| SCHEMBL9927399 | 0.88 | TSHR (0.54) | TSHRSMN1; SMN2SERPINE1LMNAMEN1 | |
| SCHEMBL16248436 | 0.88 | TSHR (0.62) | TSHRSMN1; SMN2ABCB11CYP3A4ADRA2B | |
| SCHEMBL17932907 | 0.88 | TSHR (0.62) | TSHRSMN1; SMN2ABCB11CYP3A4ADRA2B | |
| SCHEMBL1372828 | 0.88 | TSHR (0.62) | TSHRSMN1; SMN2ABCB11CYP3A4ADRA2B | |
| SCHEMBL17798243 | 0.86 | SMN1; SMN2 (0.68) | TSHRSMN1; SMN2SERPINE1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL28152832 | 0.86 | TSHR (0.61) | TSHRSMN1; SMN2ABCB11CYP3A4ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7479516-B2 | Nanocomposites and methods thereto | ZYVEX PERFORMANCE MATERIALS, LLC (US) | 2009-01-20 | — | — | US | disclosed |
| US-20070265379-A1 | NANOCOMPOSITES AND METHODS THERETO | ZYVEX CORPORATION (US) | 2007-11-15 | — | — | US | disclosed |