SCHEMBL992768

SCHEMBL992768

CC(O)c1cccc(N)c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.44
CYP3A4 P08684 5/20 0.39
TSHR P16473 4/20 0.39
GABRA1 P14867 3/20 0.39
LMNA P02545 3/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
HPGD P15428 2/20 0.39
CYP1A2 P05177 2/20 0.39
GABRB2 P47870 2/20 0.39
HIF1A Q16665 2/20 0.39
FAAH O00519 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GABRB1 P18505 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104522 0.86 CYP3A4 (0.48) CD44CYP3A4TSHRGABRA1LMNA
SCHEMBL29407112 0.86 CYP3A4 (0.48) CD44CYP3A4TSHRGABRA1LMNA
SCHEMBL14081995 0.84 GABRA1 (0.52) CYP3A4TSHRGABRA1LMNAGABRG2
SCHEMBL1464678 0.82 CYP3A4 (0.39) CD44CYP3A4TSHRGABRA1LMNA
SCHEMBL29609748 0.81 CYP3A4 (0.43) CYP3A4TSHRGABRA1LMNAGABRG2
SCHEMBL2190380 0.81 CYP3A4 (0.43) CYP3A4TSHRGABRA1LMNAGABRG2
SCHEMBL129026 0.81 CYP3A4 (0.43) CYP3A4TSHRGABRA1LMNAGABRG2
SCHEMBL3482836 0.81 CD44 (0.48) CD44CYP3A4TSHRGABRA1LMNA
SCHEMBL3725041 0.81 CYP3A4 (0.43) CYP3A4TSHRGABRA1LMNAGABRG2
SCHEMBL10624727 0.80 GABRA1 (0.46) CYP3A4TSHRGABRA1LMNAGABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5061289-A AS DEVELOPERS WELLA AKTIENGESELLSCHAFT (DE) 1991-10-29 US claimed
US-4762875-A Water based printing inks for plastic and metal surfaces GOLD MARVIN H (US) 1988-08-09 US claimed
US-4762865-A Epoxy coatings for computer hard disks and metal coil decoration and protection GOLD MARVIN H (US) 1988-08-09 US claimed
US-4652388-A WATER BASED DISPERSION; ADHESIVE PLASTICIZER AND POLYMER GOLD MARVIN H (US) 1987-03-24 US claimed
JP-11071246-A None JP disclosed
EP-2454253-A1 AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES Merck Patent GmbH (DE) 2012-05-23 EP disclosed
WO-2011006567-A1 AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES MERCK PATENT GMBH (DE) 2011-01-20 WO disclosed
EP-0706787-B1 Oxidation hair dye WELLA AG (DE) 2000-02-16 EP disclosed
JP-H1171246-A HAIR-DYEING AGENT COMPOSITION KAO CORP 1999-03-16 JP disclosed
EP-0706787-A1 Oxidation hair dye Wella Aktiengesellschaft (DE) 1996-04-17 EP disclosed