Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959889 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL838252 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL523320 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8401255 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL3116771 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL3116768 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL406864 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL406865 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1482927 | 0.80 | HTT (0.59) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL30221008 | 0.80 | HTT (0.59) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463279-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-06-13 | — | — | EP | disclosed |