SCHEMBL992851

SCHEMBL992851

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nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.42
S1PR3 Q99500 1/20 0.42
LTA4H P09960 2/20 0.41
BMP1 P13497 3/20 0.39
BHMT Q93088 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP3 P08254 2/20 0.36
GABRR1 P24046 1/20 0.36
MMP7 P09237 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16295289 1.00 S1PR1 (0.42) S1PR1S1PR3LTA4HBMP1BHMT
SCHEMBL16295014 1.00 S1PR1 (0.42) S1PR1S1PR3LTA4HBMP1BHMT
SCHEMBL30656951 0.84 BMP1 (0.50) BMP1MMP1MMP2MMP3
SCHEMBL21664134 0.82 BMP1 (0.49) BMP1MMP1MMP2MMP3
SCHEMBL14669802 0.82 BMP1 (0.49) BMP1MMP1MMP2MMP3
SCHEMBL24096068 0.81 ECE1 (0.35) BMP1
SCHEMBL10886294 0.81 ECE1 (0.35) BMP1
SCHEMBL8729439 0.81 ECE1 (0.35) BMP1
SCHEMBL16280988 0.81 SLC1A3 (0.35) BMP1MMP1MMP2MMP3
SCHEMBL12534395 0.81 SLC1A3 (0.35) BMP1MMP1MMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2106279-A2 STATIONARY PHASE GRADIENT CHROMATOGRAPHY Cryobiophysica, Inc. (US) 2009-10-07 EP claimed
US-20080179243-A1 Stationary Phase Gradient Chromatography HIRSH ALLEN 2008-07-31 US claimed
WO-2008086357-A2 STATIONARY PHASE GRADIENT CHROMATOGRAPHY CRYOBIOPHYSICA, INC. (US) 2008-07-17 WO claimed
US-20240219307-A1 APPARATUS FOR CONDUCTING CONTINUOUS INTERLEAVED ASSAYING IN A MULTI-WELL PLATE MESO SCALE TECHNOLOGIES, LLC. (US) 2024-07-04 US disclosed
US-20240159766-A1 ASSAY APPARATUSES, METHODS AND REAGENTS MESO SCALE TECHNOLOGIES, LLC. (US) 2024-05-16 US disclosed
US-11940385-B2 Apparatus for conducting continuous interleaved assaying in a multi-well plate MESO SCALE TECHNOLOGIES, LLC. (US) 2024-03-26 US disclosed
US-11892455-B2 Assay apparatuses, methods and reagents MESO SCALE TECHNOLOGIES, LLC. (US) 2024-02-06 US disclosed
US-20230357320-A1 HELICAL STAPLED PEPTIDES AND USES THEREOF PARABILIS MEDICINES, INC. 2023-11-09 US disclosed
EP-1963854-B1 ASSAY APPARATUSES, METHODS AND REAGENTS MESO SCALE TECHNOLOGIES LLC (US) 2021-02-03 EP disclosed
US-20210025896-A1 Assay Apparatuses, Methods and Reagents MESO SCALE TECHNOLOGIES, LLC. 2021-01-28 US disclosed
US-10794914-B2 Assay apparatuses, methods and reagents MESO SCALE TECHNOLOGIES, LLC (US) 2020-10-06 US disclosed
EP-2269026-A2 ASSAY APPARATUSES, METHODS AND REAGENTS Meso Scale Technologies, LLC (US) 2011-01-05 EP disclosed
US-20090263904-A1 ASSAY APPARATUSES, METHODS AND REAGENTS MESO SCALE TECHNOLOGIES, LLC 2009-10-22 US disclosed
WO-2009126303-A2 ASSAY APPARATUSES, METHODS AND REAGENTS MESO SCALE TECHNOLOGIES, LLC (US) 2009-10-15 WO disclosed
EP-2106279-A2 STATIONARY PHASE GRADIENT CHROMATOGRAPHY Cryobiophysica, Inc. (US) 2009-10-07 EP disclosed
EP-1963854-A2 ASSAY APPARATUSES, METHODS AND REAGENTS Meso Scale Technologies, LLC (US) 2008-09-03 EP disclosed
US-20080179243-A1 Stationary Phase Gradient Chromatography HIRSH ALLEN 2008-07-31 US disclosed
WO-2008086357-A2 STATIONARY PHASE GRADIENT CHROMATOGRAPHY CRYOBIOPHYSICA, INC. (US) 2008-07-17 WO disclosed
WO-2008057111-A2 ASSAY APPARATUSES, METHODS AND REAGENTS MESO SCALE TECHNOLOGIES, LLC (US) 2008-05-15 WO disclosed
US-20070231217-A1 Assay apparatuses, methods and reagents UNITED STATES GOVERNMENT; DEFENSE THREAT REDUCTION AGENCY 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357320-A1 HELICAL STAPLED PEPTIDES AND USES THEREOF ESRRB, ESR1, ESRRA S1PR1 3192/4885S1PR3 3213/4885LTA4H 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.