SCHEMBL9928663

SCHEMBL9928663

CN(CC(O)CO)C(=O)c1c(I)c(NC(=O)CO)c(I)c(C(=O)CNCCOCCN(C)C(=O)c2c(I)c(NC(=O)CO)c(I)c(C(=O)N(C)CC(O)CO)c2I)c1I

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9928664 0.91 LMNA (0.59) LMNA
SCHEMBL13885446 0.83 LMNA (0.65) LMNA
SCHEMBL3051965 0.82 LMNA (0.65) LMNA
SCHEMBL3065802 0.82 LMNA (0.44) LMNA
SCHEMBL9976300 0.81 LMNA (0.60) LMNA
SCHEMBL13246453 0.80 LMNA (0.61) LMNA
SCHEMBL13247491 0.80 LMNA (0.61) LMNA
SCHEMBL10044866 0.79 LMNA (0.58) LMNA
SCHEMBL13138908 0.79 LMNA (0.62) LMNA
SCHEMBL13885042 0.79 LMNA (0.66) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202511-B2 Contrast agents GE HEALTHCARE AS (NO) 2012-06-19 US disclosed