Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 8/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462325 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL31462328 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL7823505 | 0.78 | — | — | |
| SCHEMBL5748868 | 0.78 | — | — | |
| SCHEMBL16143873 | 0.76 | ALDH1A1 (0.35) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL7920489 | 0.76 | ALDH1A1 (0.35) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL905441 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL7640876 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL19833143 | 0.73 | TSHR (0.36) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL2682007 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697827-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | W. R. GRACE & CO.-CONN (US) | 2014-04-15 | — | — | US | disclosed |
| EP-2655434-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | Dow Global Technologies LLC (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-8383540-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-26 | — | — | US | disclosed |
| WO-2012087535-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |