SCHEMBL993030

SCHEMBL993030

COc1ccc(C(OC[C@H]2O[C@@H](n3cc(C)c(=O)n(COCC(C)c4ccccc4[N+](=O)[O-])c3=O)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYMP P19971 2/20 0.40
TYMS P04818 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993419 0.85 TYMS (0.33) TYMS
SCHEMBL994823 0.85 TYMS (0.34) TYMS
SCHEMBL12932123 0.84 LMNA (0.34) TYMS
SCHEMBL12932117 0.84 LMNA (0.34) TYMS
SCHEMBL992342 0.84 LMNA (0.34) TYMS
SCHEMBL993031 0.83
SCHEMBL4627707 0.81 TYMS (0.41) TYMPTYMS
SCHEMBL19222612 0.77 TYMP (0.43) TYMPTYMS
SCHEMBL17026404 0.76 TYMP (0.41) TYMPTYMS
SCHEMBL17026403 0.76 TYMP (0.41) TYMPTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009607-A1 METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END THE UNIVERSITY OF TOKYO (JP) 2011-01-13 US disclosed
EP-2270142-A1 METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END The University of Tokyo (JP) 2011-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009607-A1 METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END POLB, POLL, POLN TYMP 63/4885TYMS 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.