Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 11/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 11/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 11/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 9/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 9/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 9/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 9/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14250022 | 0.84 | PARP1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL1439122 | 0.83 | PARP1 (0.41) | — | |
| SCHEMBL9898861 | 0.80 | SYK (0.36) | KDM5AHASPIN | |
| SCHEMBL29984777 | 0.80 | SYK (0.36) | KDM5AHASPIN | |
| SCHEMBL28367235 | 0.78 | NR4A2 (0.36) | PRKAG1PRKAA1PRKAB1HASPIN | |
| SCHEMBL6287186 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL14406911 | 0.73 | NTRK1 (0.44) | F7F3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL27185501 | 0.73 | PARP1 (0.45) | KDM4EHSD17B10ASPHKDM8 | |
| SCHEMBL29893978 | 0.73 | PARP1 (0.45) | KDM4EHSD17B10ASPHKDM8 | |
| SCHEMBL22050802 | 0.72 | KDM4E (0.45) | F7F3PRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103582644-B | Phthalazinone-Pyrrolopyrimidine Carboxamide Derivatives | 塔科达有限责任公司 | 2016-07-20 | — | — | CN | disclosed |
| US-20120157439-A1 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157439-A1 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | BRAF, RAF1, ARAF | F7 1925/4885F3 443/4885PRKAG1 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.