Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968724 | 0.89 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL9929409 | 0.83 | MCHR1 (0.64) | MCHR1HTR5A | |
| SCHEMBL9968694 | 0.83 | MCHR1 (1.00) | MCHR1 | |
| Hydrochloric Acid SCHEMBL9931331 | 0.82 | MCHR1 (0.98) | MCHR1 | |
| SCHEMBL9929888 | 0.77 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL9931287 | 0.76 | MCHR1 (0.70) | MCHR1 | |
| SCHEMBL9929613 | 0.76 | MCHR1 (0.64) | MCHR1 | |
| SCHEMBL9929427 | 0.76 | MCHR1 (0.77) | MCHR1 | |
| SCHEMBL9963944 | 0.74 | MCHR1 (0.62) | MCHR1HTR5A | |
| SCHEMBL9930728 | 0.74 | MCHR1 (0.89) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993765-B2 | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120157460-A1 | TETRAHYDRO-AZACARBOLINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157460-A1 | TETRAHYDRO-AZACARBOLINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USES THEREOF | MCHR1, MCHR2, MC5R | MCHR1 1/4885HTR5A 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.