Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212313 | 0.83 | AOC3 (0.53) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL23931092 | 0.83 | AOC3 (0.53) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL8597522 | 0.80 | IDO1 (0.55) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL3237585 | 0.79 | AOC3 (0.53) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL8910900 | 0.79 | AOC3 (0.56) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL11331407 | 0.78 | AOC3 (0.49) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL30883 | 0.77 | AOC3 (0.55) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL16033385 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2POLBCYP1A2KDM4ECTDSP1 | |
| SCHEMBL7002838 | 0.76 | AOC3 (0.46) | AOC3SMN1; SMN2CHRM2OPRK1POLB | |
| SCHEMBL2027829 | 0.76 | AOC3 (0.46) | AOC3SMN1; SMN2CHRM2OPRK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247927-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-12-10 | — | — | WO | claimed |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | THE UNIVERSITY OF TOKYO (JP) | 2011-01-13 | — | — | US | claimed |
| EP-2270142-A1 | METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END | The University of Tokyo (JP) | 2011-01-05 | — | — | EP | claimed |
| EP-4006135-A1 | PRIMER, DEVICE FOR PRODUCING DOUBLE-STRANDED DNA USING SAME, AND METHOD FOR PRODUCING DOUBLE-STRANDED DNA | Japan Science and Technology Agency (JP) | 2022-06-01 | — | — | EP | disclosed |
| EP-4006041-A1 | PRIMER, APPARATUS FOR PRODUCING DOUBLE-STRANDED DNA USING SAME, AND METHOD FOR PRODUCING DOUBLE-STRANDED DNA | Japan Science and Technology Agency (JP) | 2022-06-01 | — | — | EP | disclosed |
| US-20220162687-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2022-05-26 | — | — | US | disclosed |
| CN-114302965-A | Primer, double-stranded DNA production apparatus using the same, and double-stranded DNA production method | 国立研究开发法人科学技术振兴机构 | 2022-04-08 | — | — | CN | disclosed |
| CN-114174509-A | Primer, double-stranded DNA production apparatus using the same, and double-stranded DNA production method | 国立研究开发法人科学技术振兴机构 | 2022-03-11 | — | — | CN | disclosed |
| WO-2021020562-A1 | PRIMER, DEVICE FOR PRODUCING DOUBLE-STRANDED DNA USING SAME, AND METHOD FOR PRODUCING DOUBLE-STRANDED DNA | 国立研究開発法人科学技術振興機構 | 2021-02-04 | — | — | WO | disclosed |
| WO-2021020561-A1 | PRIMER, APPARATUS FOR PRODUCING DOUBLE-STRANDED DNA USING SAME, AND METHOD FOR PRODUCING DOUBLE-STRANDED DNA | 国立研究開発法人科学技術振興機構 | 2021-02-04 | — | — | WO | disclosed |
| WO-2020247927-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-12-10 | — | — | WO | disclosed |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | THE UNIVERSITY OF TOKYO (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2270142-A1 | METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END | The University of Tokyo (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | POLB, POLL, POLN | AOC3 2379/4885SMN1; SMN2 4115/4885CHRM2 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.