SCHEMBL9935835

SCHEMBL9935835

O=S(=O)(Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1)c1ccc(F)cc1.O=S(=O)(Nc1cc(Cl)ccc1NS(=O)(=O)c1c(Cl)cccc1Cl)c1cc2ccccc2o1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9932117 0.85 CCR2 (1.00) CCR2
SCHEMBL9930787 0.85 CCR2 (1.00) CCR2
SCHEMBL9931142 0.84 CCR2 (0.73) CCR2
SCHEMBL9930486 0.82 CCR2 (1.00) CCR2
SCHEMBL9930913 0.82 CCR2 (1.00) CCR2
SCHEMBL9930857 0.81 CCR2 (0.69) CCR2
SCHEMBL9931480 0.78 CCR2 (0.74) CCR2
SCHEMBL9930547 0.78 CCR2 (0.73) CCR2
SCHEMBL9931533 0.78 CCR2 (0.75) CCR2
SCHEMBL9931494 0.77 CCR2 (1.00) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651901-A1 NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS Allergan, Inc. (US) 2013-10-23 EP disclosed
WO-2012082633-A1 NOVEL 1,2- BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS ALLERGAN, INC. (US) 2012-06-21 WO disclosed