Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940363 | 0.92 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL15282991 | 0.90 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL9936294 | 0.90 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL9936479 | 0.89 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL9936126 | 0.85 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL9936702 | 0.84 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL15283088 | 0.83 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL15282985 | 0.82 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL9936281 | 0.82 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL9940147 | 0.82 | DGAT1 (0.55) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651915-A1 | CONTINUOUS ARYCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012081736-A1 | CONTINUOUS ARYCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-06-21 | — | — | WO | disclosed |