Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965004 | 0.88 | MAPT (0.39) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9964993 | 0.87 | MAPT (0.40) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9964979 | 0.76 | CYP19A1 (0.42) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9965021 | 0.75 | MEN1 (0.41) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9964988 | 0.75 | KDM4E (0.51) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9965008 | 0.74 | SMN1; SMN2 (0.44) | KDM4EMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL9964968 | 0.73 | MAPT (0.49) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9964958 | 0.73 | SMN1; SMN2 (0.46) | KDM4EMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL9964961 | 0.72 | MAPT (0.35) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL9964984 | 0.72 | ROCK2 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651516-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080285-A2 | DYE COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |