SCHEMBL9936848

SCHEMBL9936848

CCOCCOC(=O)C(F)F

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
TSHR P16473 4/20 0.58
THRB P10828 1/20 0.50
HSD17B10 Q99714 3/20 0.39
GAA P10253 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9937323 0.87 ALDH1A1 (0.43) ALDH1A1TSHRTHRBACHE
SCHEMBL9937353 0.84 ALDH1A1 (0.56) ALDH1A1TSHRTHRBHSD17B10GAA
SCHEMBL9936838 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTHRBHSD17B10GAA
SCHEMBL4676252 0.79 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHSD17B10GAA
SCHEMBL10233231 0.79 ALDH1A1 (0.60) ALDH1A1TSHRTHRBHSD17B10GAA
SCHEMBL6588379 0.78
SCHEMBL238384 0.78
SCHEMBL5996548 0.77 ALDH1A1 (0.58) ALDH1A1TSHRTHRBHSD17B10GAA
SCHEMBL9122415 0.77 ALDH1A1 (0.64) ALDH1A1TSHRTHRBHSD17B10GAA
SCHEMBL16021805 0.77 ALDH1A1 (0.58) ALDH1A1TSHRTHRBHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9472813-B2 Battery electrolyte solution containing certain ester-based solvents, and batteries containing such an electrolyte solution DOW GLOBAL TECHNOLOGIES LLC (US) 2016-10-18 US disclosed
CN-103262329-B Battery electrolyte solution containing certain ester-based solvents and battery containing such electrolyte solution DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-10 CN disclosed
EP-2652832-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION Dow Global Technologies LLC (US) 2013-10-23 EP disclosed
US-20130260229-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-03 US disclosed
CN-103262329-A Battery electrolyte solution containing certain ester-based solvents and battery containing such electrolyte solution DOW GLOBAL TECHNOLOGIES INC 2013-08-21 CN disclosed
WO-2012082760-A1 BATTERY ELECTROLYTE SOLUTION CONTAINING CERTAIN ESTER-BASED SOLVENTS, AND BATTERIES CONTAINING SUCH AN ELECTROLYTE SOLUTION DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-21 WO disclosed