Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13798671 | 0.94 | TLR7 (0.71) | TLR7 | |
| SCHEMBL13798674 | 0.94 | TLR7 (0.71) | TLR7 | |
| SCHEMBL30164530 | 0.94 | TLR7 (0.71) | TLR7 | |
| SCHEMBL13798675 | 0.94 | TLR7 (0.70) | TLR7 | |
| SCHEMBL9936854 | 0.93 | TLR7 (0.62) | TLR7 | |
| SCHEMBL4139909 | 0.93 | TLR7 (0.79) | TLR7 | |
| SCHEMBL12048762 | 0.93 | TLR7 (0.71) | TLR7 | |
| SCHEMBL13798673 | 0.92 | TLR7 (0.68) | TLR7 | |
| SCHEMBL13798672 | 0.92 | TLR7 (0.68) | TLR7 | |
| SCHEMBL16256477 | 0.92 | TLR7 (0.68) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651943-B1 | PURINE DERIVATIVES | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-8895570-B2 | Purine derivatives | ASTRAZENECA AB (SE) | 2014-11-25 | — | — | US | disclosed |
| WO-2012080730-A1 | PURINE DERIVATIVES | ASTRAZENECA AB (SE) | 2012-06-21 | — | — | WO | disclosed |