Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679220 | 0.83 | TSHR (0.39) | TSHRTHRBLMNACYP2D6CYP1A2 | |
| SCHEMBL3267819 | 0.82 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL239022 | 0.81 | TSHR (0.43) | TSHRTHRBALDH1A1 | |
| SCHEMBL3855601 | 0.79 | TSHR (0.44) | TSHRTHRBALDH1A1POLB | |
| SCHEMBL196351 | 0.78 | TSHR (0.49) | TSHRTHRBLMNAALDH1A1POLB | |
| SCHEMBL5533901 | 0.78 | THRB (0.44) | TSHRTHRBALDH1A1MEN1KMT2A | |
| SCHEMBL17049497 | 0.78 | THRB (0.44) | TSHRTHRBALDH1A1MEN1KMT2A | |
| SCHEMBL222838 | 0.78 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL36100 | 0.77 | TSHR (0.45) | TSHRTHRBLMNAALDH1A1 | |
| SCHEMBL5356713 | 0.77 | THRB (0.58) | TSHRTHRBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652075-A2 | PERSONAL CARE COMPOSITIONS INCLUDING AQUEOUS COMPOSITIONS OF VISCOELASTIC SURFACTANTS AND HYDROPHOBICALLY MODIFIED POLYMERS | Akzo Nobel Chemicals International B.V. (NL) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080383-A2 | PERSONAL CARE COMPOSITIONS INCLUDING AQUEOUS COMPOSITIONS OF VISCOELASTIC SURFACTANTS AND HYDROPHOBICALLY MODIFIED POLYMERS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2012-06-21 | — | — | WO | disclosed |