Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.71 |
| ▸ | CCR5 | P51681 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993339 | 0.90 | CCR1 (1.00) | CCR1CHRM2CCR5 | |
| SCHEMBL992432 | 0.89 | CCR1 (0.81) | CCR1CHRM2CCR5 | |
| SCHEMBL5725969 | 0.88 | CCR1 (0.64) | CCR1CHRM2CCR5 | |
| SCHEMBL9910989 | 0.85 | CCR1 (0.87) | CCR1CHRM2CCR5 | |
| SCHEMBL4071787 | 0.84 | CCR1 (0.82) | CCR1 | |
| SCHEMBL993584 | 0.83 | CCR1 (0.83) | CCR1CHRM2CCR5 | |
| SCHEMBL30059121 | 0.83 | CCR1 (1.00) | CCR1CHRM2CCR5 | |
| SCHEMBL995030 | 0.83 | CCR1 (1.00) | CCR1CHRM2CCR5 | |
| SCHEMBL29709355 | 0.83 | CCR1 (1.00) | CCR1CHRM2CCR5 | |
| SCHEMBL993077 | 0.81 | CCR1 (0.83) | CCR1CHRM2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7887840-B2 | Bioavailability of low- solubility drugs | BEND RESEARCH, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| EP-2275091-A1 | Pharmaceutical compositions comprising adsorbates of an amorphous drug | Pfizer Products Inc. (US) | 2011-01-19 | — | — | EP | disclosed |