Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.76 |
| ▸ | CCR5 | P51681 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993077 | 0.91 | CCR1 (0.83) | CCR1CHRM2CCR5 | |
| SCHEMBL993754 | 0.90 | CCR1 (0.82) | CCR1CHRM2CCR5 | |
| SCHEMBL993005 | 0.90 | CCR1 (0.81) | CCR1CHRM2CCR5 | |
| SCHEMBL992432 | 0.89 | CCR1 (0.81) | CCR1CHRM2CCR5 | |
| SCHEMBL9910989 | 0.88 | CCR1 (0.87) | CCR1CHRM2CCR5 | |
| SCHEMBL993584 | 0.88 | CCR1 (0.83) | CCR1CHRM2CCR5 | |
| SCHEMBL5725022 | 0.88 | CCR1 (0.78) | CCR1CHRM2CCR5 | |
| SCHEMBL29709355 | 0.86 | CCR1 (1.00) | CCR1CHRM2CCR5 | |
| SCHEMBL995030 | 0.86 | CCR1 (1.00) | CCR1CHRM2CCR5 | |
| SCHEMBL30059121 | 0.86 | CCR1 (1.00) | CCR1CHRM2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8147872-B2 | Pharmaceutical compositions of drugs and neutralized acidic polymers | Bend Reseach, Inc. (US) | 2012-04-03 | — | — | US | disclosed |
| US-7887840-B2 | Bioavailability of low- solubility drugs | BEND RESEARCH, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| EP-2275091-A1 | Pharmaceutical compositions comprising adsorbates of an amorphous drug | Pfizer Products Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| US-20060003011-A1 | Pharmaceutical compositions of drugs and neutralized acidic polymers | PFIZER INC | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060003011-A1 | Pharmaceutical compositions of drugs and neutralized acidic polymers | PDE7A, CA6, PDE9A | CCR1 1188/4885CHRM2 2122/4885CCR5 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.