Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK2 | P52789 | 17/20 | 0.71 |
| ▸ | HK1 | P19367 | 16/20 | 0.71 |
| ▸ | GCK | P35557 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938050 | 1.00 | HK2 (0.71) | HK2HK1GCKKDM4EALDH1A1 | |
| SCHEMBL9937446 | 0.69 | HK1 (1.00) | HK2HK1GCK | |
| SCHEMBL9938423 | 0.68 | HK2 (0.80) | HK2HK1GCK | |
| SCHEMBL4607774 | 0.67 | MCL1 (0.46) | ALDH1A1LMNA | |
| SCHEMBL9937688 | 0.62 | HK1 (0.69) | HK2HK1GCKLMNAPOLB | |
| SCHEMBL9937695 | 0.62 | HK1 (0.69) | HK2HK1GCKLMNAPOLB | |
| SCHEMBL9938663 | 0.61 | HK1 (0.73) | HK2HK1GCK | |
| SCHEMBL15881071 | 0.61 | MCL1 (0.53) | KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9938774 | 0.61 | HK1 (0.60) | HK2HK1GCKKDM4EALDH1A1 | |
| SCHEMBL9971331 | 0.60 | HK1 (0.73) | HK2HK1GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |