Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 13/20 | 0.69 |
| ▸ | HK2 | P52789 | 13/20 | 0.69 |
| ▸ | GCK | P35557 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937695 | 1.00 | HK1 (0.69) | HK1HK2GCKPOLBLMNA | |
| SCHEMBL9971331 | 0.87 | HK1 (0.73) | HK1HK2GCK | |
| SCHEMBL9937801 | 0.86 | HK1 (0.52) | HK1HK2GCKPOLBLMNA | |
| SCHEMBL9937795 | 0.84 | HK1 (0.49) | HK1HK2GCK | |
| SCHEMBL9937441 | 0.79 | HK1 (1.00) | HK1HK2GCK | |
| SCHEMBL9937446 | 0.79 | HK1 (1.00) | HK1HK2GCK | |
| SCHEMBL9938769 | 0.78 | HK1 (0.60) | HK1HK2GCKEPHX2NR1H4 | |
| SCHEMBL9938774 | 0.78 | HK1 (0.60) | HK1HK2GCKEPHX2NR1H4 | |
| SCHEMBL9938423 | 0.76 | HK2 (0.80) | HK1HK2GCK | |
| SCHEMBL9938427 | 0.76 | HK2 (0.80) | HK1HK2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |