⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652123 | 0.88 | TAAR1 (0.55) | — | |
| SCHEMBL31538874 | 0.86 | TAAR1 (0.53) | — | |
| SCHEMBL144121 | 0.78 | — | — | |
| SCHEMBL400685 | 0.78 | — | — | |
| SCHEMBL11109453 | 0.78 | — | — | |
| SCHEMBL6075599 | 0.78 | — | — | |
| SCHEMBL2030841 | 0.78 | TAAR1 (0.71) | — | |
| SCHEMBL37659 | 0.77 | — | — | |
| SCHEMBL8987661 | 0.76 | MAPT (0.48) | — | |
| SCHEMBL14376819 | 0.76 | MAPT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268015-B2 | Method for decolorizing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2012-09-18 | — | — | US | claimed |
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | HENKEL AG & CO. KGAA (DE) | 2011-10-13 | — | — | US | claimed |
| CN-102199637-A | Method for preparing (S)-3-hydroxyl-3-(2-thienyl)-propionitrile by microbial transformation | UNIV ZHEJIANG TECHNOLOGY | 2011-09-28 | — | — | CN | claimed |
| US-5856501-A | Synthesis of thiazole derivatives | ALBEMARLE CORPORATION (US) | 1999-01-05 | — | — | US | claimed |
| WO-1998040368-A1 | SYNTHESIS OF THIAZOLE DERIVATIVES | ALBEMARLE CORPORATION (US) | 1998-09-17 | — | — | WO | claimed |
| US-4942243-A | Process for preparing N\"-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]guanidine | HANIL PHARMACEUTICAL IND., CO., LTD. (KR) | 1990-07-17 | — | — | US | claimed |
| CN-105039361-B | Carbonyl reduction enzyme gene, codase, carrier, bacterial strain and application | 浙江工业大学 | 2019-08-30 | — | — | CN | disclosed |
| US-10131908-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-11-20 | — | — | US | disclosed |
| CN-107024834-A | Compound and coloured composition | 住友化学株式会社 | 2017-08-08 | — | — | CN | disclosed |
| US-20150080457-A1 | 5' PHOSPHATE MIMICS | BANK OF AMERICA, N.A. | 2015-03-19 | — | — | US | disclosed |
| US-8927513-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8268015-B2 | Method for decolorizing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-4847241-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4822775-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4810800-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-03-07 | — | — | US | disclosed |
| US-4752613-A | Sulphonamidothienylcarboxylic acid compounds | E. R. SQUIBB & SONS, INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0215297-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4219659-A | Process for the preparation of thiophene derivatives and thiophene derivatives obtained therethrough | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-08-26 | — | — | US | disclosed |
| US-4197310-A | ANTIARTHRITIC, ANTIINFLAMMATORY, PREVENT JOINT DETERIORATION | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |