Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538874 | 0.94 | TAAR1 (0.53) | TAAR1TSHRMAPTCTSCADRA2A | |
| SCHEMBL993814 | 0.88 | — | — | |
| SCHEMBL8987661 | 0.80 | MAPT (0.48) | TAAR1MAPTCTSCMEN1KMT2A | |
| SCHEMBL20135772 | 0.80 | TAAR1 (0.73) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL20146704 | 0.80 | TAAR1 (0.73) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL10722210 | 0.80 | TAAR1 (0.55) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL144587 | 0.80 | TAAR1 (0.55) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL8571535 | 0.78 | TAAR1 (0.70) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL6734915 | 0.78 | TAAR1 (0.70) | TAAR1TSHRADRA2AADRA2BADRA2C | |
| SCHEMBL7116263 | 0.78 | TAAR1 (0.70) | TAAR1TSHRADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-0171213-B1 | SPIRO-IMIDAZOLONES FOR TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4680306-A | Sprio-imidazolones for treatment of diabetes complications | PFIZER INC. (US) | 1987-07-14 | — | — | US | disclosed |
| WO-1986000807-A1 | SPIRO-IMIDAZOLONES FOR TREATMENT OF DIABETES COMPLICATIONS | PFIZER INC. (US) | 1986-02-13 | — | — | WO | disclosed |
| EP-0171213-A1 | Spiro-imidazolones for treatment of diabetic complications | PFIZER INC. (US) | 1986-02-12 | — | — | EP | disclosed |