⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761620 | 0.91 | — | — | |
| SCHEMBL1844002 | 0.80 | — | — | |
| SCHEMBL1469615 | 0.79 | FAAH (0.67) | — | |
| SCHEMBL1470382 | 0.79 | FAAH (0.58) | — | |
| SCHEMBL28473138 | 0.76 | FAAH (0.72) | — | |
| SCHEMBL28311490 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL21582585 | 0.73 | FAAH (0.46) | — | |
| SCHEMBL1470276 | 0.71 | FAAH (0.47) | — | |
| SCHEMBL12136466 | 0.71 | — | — | |
| SCHEMBL3294656 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-10-06 | — | — | US | disclosed |
| EP-3892610-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT | The Scripps Research Institute (US) | 2021-10-13 | — | — | EP | disclosed |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-12 | — | — | US | disclosed |
| EP-3151817-B1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | SCRIPPS RESEARCH INST (US) | 2021-03-03 | — | — | EP | disclosed |
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-24 | — | — | US | disclosed |
| CN-111689929-A | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-09-22 | — | — | CN | disclosed |
| US-10765645-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-08 | — | — | US | disclosed |
| CN-106659700-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-07-10 | — | — | CN | disclosed |
| WO-2015188120-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
| US-9120818-B2 | Process and intermediates for preparing macrolactams | MERCK SHARP & DOHME CORP. (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120818-B2 | Process and intermediates for preparing macrolactams | MERCK SHARP & DOHME CORP. (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120818-B2 | Process and intermediates for preparing macrolactams | MERCK SHARP & DOHME CORP. (US) | 2015-09-01 | — | — | US | disclosed |
| EP-2651884-A2 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | Merck Sharp & Dohme Corp. (US) | 2013-10-23 | — | — | EP | disclosed |
| US-20130274463-A1 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. | 2013-10-17 | — | — | US | disclosed |
| US-20130274463-A1 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. | 2013-10-17 | — | — | US | disclosed |
| US-20130274463-A1 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. | 2013-10-17 | — | — | US | disclosed |
| WO-2012082672-A2 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012082672-A2 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. (US) | 2012-06-21 | — | — | WO | disclosed |