Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902470 | 0.63 | TDP1 (0.33) | — | |
| SCHEMBL4602159 | 0.63 | HTT (0.32) | HTTCA2 | |
| SCHEMBL4314716 | 0.62 | — | — | |
| SCHEMBL13134064 | 0.62 | — | — | |
| SCHEMBL4493627 | 0.62 | — | — | |
| SCHEMBL28987550 | 0.59 | HTT (0.32) | HTTCA2 | |
| SCHEMBL30149206 | 0.59 | HTT (0.32) | HTTCA2 | |
| SCHEMBL9698996 | 0.58 | RECQL (0.40) | — | |
| SCHEMBL9845818 | 0.57 | — | — | |
| SCHEMBL4765510 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651403-A2 | USE OF LP-PLA2 INHIBITORS IN THE TREATMENT AND PREVENTION OF EYE DISEASES | Glaxo Group Limited (GB) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080497-A2 | METHODS OF TREATMENT AND PREVENTION OF EYE DISEASES | GLAXO GROUP LIMITED (GB) | 2012-06-21 | — | — | WO | claimed |