Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258828 | 0.65 | KDM4E (0.31) | KDM4E | |
| SCHEMBL6209229 | 0.65 | — | — | |
| Caricotamide SCHEMBL6546956 | 0.63 | LDHA (0.37) | KDM4E | |
| SCHEMBL28886735 | 0.60 | — | — | |
| SCHEMBL7962187 | 0.60 | KDM4E (0.31) | KDM4E | |
| SCHEMBL9653242 | 0.58 | KDM4E (0.30) | KDM4E | |
| SCHEMBL10503987 | 0.58 | — | — | |
| SCHEMBL480878 | 0.58 | KDM4E (0.31) | KDM4E | |
| SCHEMBL480879 | 0.58 | KDM4E (0.31) | KDM4E | |
| SCHEMBL9048947 | 0.58 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651403-A2 | USE OF LP-PLA2 INHIBITORS IN THE TREATMENT AND PREVENTION OF EYE DISEASES | Glaxo Group Limited (GB) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080497-A2 | METHODS OF TREATMENT AND PREVENTION OF EYE DISEASES | GLAXO GROUP LIMITED (GB) | 2012-06-21 | — | — | WO | claimed |